British number one Johanna Konta reached the Italian Open quarter-finals with a 6-2 6-4 win over Venus Williams – her second match of the day.
Konta, 27, came from a set down to beat world number eight Sloane Stephens before overcoming seven-time Grand Slam winner Williams, now ranked 50th.
Williams was hampered by injury and an assured Konta won in 72 minutes.
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She will play Czech teenager Marketa Vondrousova or Russian Daria Kasatkina in the last eight in Rome.
Williams received a bye into the third round after sister Serena withdrewbecause of a knee injury.
Wiliams, 38, had won her past three meetings with Konta, including the 2017 Wimbledon semi-final.
Williams had her right knee strapped and, although she improved as the match wore on, Konta reached the first Premier clay court quarter-final of her career.